O Levels Biology (5090)•5090/12/M/J/18

Explanation
Lock and Key Model in Enzyme Action
Steps:
- Identify the lock and key model: enzymes bind substrates specifically like a lock and key.
- Locate the active site: it forms on the enzyme's surface for substrate binding.
- Assign roles: enzyme functions as the lock, substrate as the key.
- Match to question: active site on enzyme, lock on enzyme, key on substrate.
Why A is correct:
- In the lock and key model, the active site is on the enzyme (the lock), while the substrate is the key that fits precisely, ensuring specificity.
Why the others are wrong:
- B: Incorrectly places active site on substrate instead of enzyme.
- C: Wrongly locates active site on substrate, reversing the model.
- D: Erroneously puts active site and lock on substrate, not enzyme.
Final answer: A
Topic: Enzyme action
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