O Levels Biology (5090)•5090/12/M/J/18

Explanation
Emphysema damages alveoli, impairing oxygen diffusion
Steps:
- Both people have equal mass and exercise, so similar oxygen demand.
- Healthy person absorbs 22 cm³/min oxygen; emphysema patient only 12 cm³/min, showing reduced uptake.
- Emphysema destroys alveolar walls, reducing gas exchange surface area.
- This damage explains lower oxygen entry despite equal activity.
Why C is correct:
- Emphysema causes alveolar destruction, creating smaller, damaged alveoli that decrease diffusion surface area, limiting oxygen transfer per Fick's law of diffusion.
Why the others are wrong:
- A: Breathing rate may be similar; problem is alveolar exchange, not ventilation speed.
- B: Emphysema enlarges lungs via air trapping, increasing volume, not decreasing it.
- D: Alveoli enlarge in emphysema, but without damage emphasis, it ignores reduced efficiency from wall breakdown.
Final answer: C
Topic: Human gas exchange
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